Ergebnisse für: TRPM8

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Buch Cover TRP Channels in Health and Disease

MDPI
€ · Paperback

ion channel TRPC small molecules calcium chemical probes TRPV1 TRPV2 TRPV3 TRPV4 mucosal epithelium ulcerative colitis inflammatory bowel disease TRPM4 channel cardiovascular system physiology

Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include control of body temperature, transmitter release, m...

Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts

MDPI
€ · Paperback

TRP channels TRPA1 TRPM2 TRPM7 TRPM8 TRPV1 TRPV3 cancer capsaicin diabetes obesity pain permanent analgesia resiniferatoxin respiratory disorders

The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a “hot” new field of basic research and launched drug discovery efforts into the larg...

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