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The predicted shortage of fossil fuels is likely to have a negative influence on the availability of base chemicals, like propylene required to produce important derivatives like n-butanol. The resulting increase in oil price and demand in C4 chemicals provides a good and necessary foundation for al...
Using dynamic models to describe biotechnological processes leads to a better understanding of the complex process dynamics and helps to find optimal conditions that improve the process significantly. However, the development of adequate mathematical models is generally difficult, tedious, time-cons...
Bovine respiratory disease (BRD) is the most important disease in the cattle industry with serious annual economic losses. Mannheimia haemolytica (M. haemolytica) is classified as the primary bacterial pathogen causing BRD and its leukotoxin (LKT) is the predominant virulence factor. Vaccines based ...
Die in-vivo-Proteinherstellung in Säugetierzelllinien oder in Mikroorganismen stellt heute den Goldstandard in der industriellen Synthese von biologischen Substanzen wie Medikamenten oder Antikörpern dar. Doch diese Art der Proteinerzeugung hat einige Nachteile, die sich kosten- und zeitintensiv a...
This detailed volume presents a series of protocols dealing with different aspects of inclusion body (IB) processing, from cloning procedures to purification of refolded product. Commencing with chapters on upstream processing, looking into different expression strategies for IB production, the book...
Nowadays, we are witnessing highly dynamic research activities related to the intriguing field of biodegradable materials with plastic-like properties. These activities are stimulated by the strengthened public awareness of prevailing ecological issues connected to growing piles of plastic waste and...
This detailed volume presents a series of protocols dealing with different aspects of inclusion body (IB) processing, from cloning procedures to purification of refolded product. Commencing with chapters on upstream processing, looking into different expression strategies for IB production, the book...
Durch den weltweit steigenden Bedarf an tierischem Protein gewinnt die mikrobielle Produktion funktioneller Lebensmittelinhaltsstoffe (Präzisionsfermentation) an Bedeutung. Das Molkenprotein β-Lactoglobulin (BLG) besitzt zwei konservierte Disulfidbrücken und eine freie Thiol-Gruppe und dient als ...
This detailed volume presents a series of protocols dealing with different aspects of inclusion body (IB) processing, from cloning procedures to purification of refolded product. Commencing with chapters on upstream processing, looking into different expression strategies for IB production, the book...
Durch den weltweit steigenden Bedarf an tierischem Protein gewinnt die mikrobielle Produktion funktioneller Lebensmittelinhaltsstoffe (Präzisionsfermentation) an Bedeutung. Das Molkenprotein β-Lactoglobulin (BLG) besitzt zwei konservierte Disulfidbrücken und eine freie Thiol-Gruppe und dient als ...
Cis,cis-muconic acid receives increasing interest to be produced from renewables. Catabolic microbial pathways can be tailored to accumulate cis,cis-muconic acid from a range of aromatic compounds. A renewable, sustainable and under-valued resource for aromatics is lignin. In this work, using hydrot...
The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and ...