Fungi Bioactive Metabolites
Integration of Pharmaceutical Applications
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Beschreibung
This book presents the exploration and exploitation of various bioactive metabolites obtained from fungi isolated from diverse habitats for pharmaceutical applications. Various fungal sources have been brought under one umbrella ranging from endophytes, marine fungi, endolichenic fungi to fungi existing in the extremophilic conditions like desert and Antarctica and Artic environment. The book tries to cover maximally the range of the pharmaceutical applications wherein these bioactive agents from fungi have been exploited or are in the clinical pipelines and primarily include antibacterial, antifungal, antibiofilm, anticancer, antioxidant, autoimmunological, anti-inflammatory, and anti-thrombotic diseases. The book further emphasizes on the novel strategies to screen or enhance secondary metabolite production. Some other topics includes peptides, nonpeptides drugs, pigments, and enhancement of production of Echinocandin and Kojic acid. The role of bioinformatics in drug discovery and biotransformations have also been discussed.
This book is going to be a comprehensive treatise and a valuable source for mycologists, biotechnologists, microbiologists, biotechnologists, and undertaking research in pharmaceutical sector as well as academia in setting up their research aspirations for using fungi in the process of drug discovery and development.
This book presents the exploration and exploitation of various bioactive metabolites obtained from fungi isolated from diverse habitats for pharmaceutical applications. Various fungal sources have been brought under one umbrella ranging from endophytes, marine fungi, endolichenic fungi to fungi existing in the extremophilic conditions like desert and Antarctica and Artic environment. The book tries to cover maximally the range of the pharmaceutical applications wherein these bioactive agents from fungi have been exploited or are in the clinical pipelines and primarily include antibacterial, antifungal, antibiofilm, anticancer, antioxidant, autoimmunological, anti-inflammatory, and anti-thrombotic diseases. The book further emphasizes on the novel strategies to screen or enhance secondary metabolite production. Some other topics includes peptides, nonpeptides drugs, pigments, and enhancement of production of Echinocandin and Kojic acid. The role of bioinformatics in drug discovery and biotransformations have also been discussed.
This book is going to be a comprehensive treatise and a valuable source for mycologists, biotechnologists, microbiologists, biotechnologists, and undertaking research in pharmaceutical sector as well as academia in setting up their research aspirations for using fungi in the process of drug discovery and development.
Includes the full exploration and application of fungal secondary metabolites Addresses Biotechnological interventions such as epigenetic modifications, co-culture, OSMAC, CRISPER and mutagenesis Gives an outlook on the future of drug discovery
Autor*in
Sunil Kumar Deshmukh
Themen in »Fungi Bioactive Metabolites«
fungal diversity marine fungi Antibacterial Metabolic disorders fungal bioactives pathogenic fungi