Protein-Protein Interactions
Pathophysiological and Therapeutic Aspects: Volume II
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Beschreibung
The second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases.
The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases.
Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.
The second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases.
The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases.
Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.
Discusses abnormal protein-protein interactions that are involved in various diseases Provides a comprehensive account of current state-of-art in the discovery of small molecules inhibiting PPIs Presents hosts and pathogens PPIs underlying the pathophysiology of infectious diseases
Autor*in
Krishna Mohan Poluri
Themen in »Protein-Protein Interactions«
Protein-protein interactions network Disease pathophysiology Computer aided drug design High-throughput screening Small molecule inhibitors