Multiscale Dynamics of Inhaled Particles: From Respiratory Deposition to Systemic Distribution
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Beschreibung
This book provides a comprehensive and integrated overview of the journey of inhaled particles, from their characterization and deposition in the respiratory tract to their interactions with biological barriers like mucus and pulmonary surfactant, and finally, their systemic distribution and clearance. Bridging the fields of respiratory physiology, aerosol science, computational fluid dynamics, molecular biophysics, and pharmacokinetics, it offers a systematic framework for understanding both therapeutic aerosol delivery and the health risks of environmental pollutants. This volume is an essential reference for graduate students, researchers, and professionals working on inhaled drug delivery, inhalation toxicology, and the dynamics of airborne particles in the human body.
This book provides a comprehensive and integrated overview of the journey of inhaled particles, from their characterization and deposition in the respiratory tract to their interactions with biological barriers like mucus and pulmonary surfactant, and finally, their systemic distribution and clearance. Bridging the fields of respiratory physiology, aerosol science, computational fluid dynamics, molecular biophysics, and pharmacokinetics, it offers a systematic framework for understanding both therapeutic aerosol delivery and the health risks of environmental pollutants. This volume is an essential reference for graduate students, researchers, and professionals working on inhaled drug delivery, inhalation toxicology, and the dynamics of airborne particles in the human body.
Reports numerical methods to solve particle dynamics in different scales and application in respiratory multi-phase flow Provides overall understanding in the multiphase flows related to the respiratory flow mechanics and biomechanics Presents overall understanding in the multiphase flows related to the respiratory flow mechanics and biomechanics
Autor*in
Xinguang Cui
Themen in »Multiscale Dynamics of Inhaled Particles: From Respiratory Deposition to Systemic Distribution«
Human respiratory system Multi-scale dynamics Inhaled particles Numerical methods Theory and applications