Practical Guide to Hereditary Breast and Ovarian Cancer V
Annual Meeting of the Japanese Organization of Hereditary Breast and Ovarian Cancer 2025
Buch in deiner Nähe kaufen
Beschreibung
This book is a curated collection of research and perspectives on Hereditary Breast and Ovarian Cancer (HBOC). Due to the shared genetic basis of these conditions—particularly mutations in the BRCA1 and BRCA2 genes—this volume also explores advancements in reproductive medicine, perinatal medicine, pancreatic cancer, prostate cancer, and more. In addition to its focus on clinical practice, the book provides updated data from nationwide registration, including the frequency of rare BRCA1/2 variants and the current status of risk-reducing surgeries. As the field rapidly evolves with the clinical development of poly (ADP-ribose) polymerase (PARP) inhibitors and the integration of BRCA1/2 genetic testing into public health insurance systems, this volume offers a comprehensive overview of the latest developments and ongoing challenges in HBOC-related care.
Readers will explore key topics such as the molecular mechanisms of carcinogenesis due to BRCA1/2 mutations, the challenges of risk-reducing mastectomy decision-making, and the future of BRCA testing in breast cancer diagnosis. Contributions from leading experts provide a comprehensive overview of healthcare for HBOPPC patients, including reproductive medicine and perinatal care, while addressing critical questions about individualized risk management and genetic counseling.
This book is an essential resource for breast surgeons and oncologists, obstetricians, gynecologists, pancreatic cancer surgeons, urologists, and genetic medicine physicians. It also serves as a valuable reference for HBOC patients, their families, and pharmaceutical professionals involved in PARP inhibitor development. By sharing the latest research and clinical practices, this volume aims to equalize and enhance HBOPPC treatment across Japan.
This book is a curated collection of research and perspectives on Hereditary Breast and Ovarian Cancer (HBOC). Due to the shared genetic basis of these conditions—particularly mutations in the BRCA1 and BRCA2 genes—this volume also explores advancements in reproductive medicine, perinatal medicine, pancreatic cancer, prostate cancer, and more. In addition to its focus on clinical practice, the book provides updated data from nationwide registration, including the frequency of rare BRCA1/2 variants and the current status of risk-reducing surgeries. As the field rapidly evolves with the clinical development of poly (ADP-ribose) polymerase (PARP) inhibitors and the integration of BRCA1/2 genetic testing into public health insurance systems, this volume offers a comprehensive overview of the latest developments and ongoing challenges in HBOC-related care.
Readers will explore key topics such as the molecular mechanisms of carcinogenesis due to BRCA1/2 mutations, the challenges of risk-reducing mastectomy decision-making, and the future of BRCA testing in breast cancer diagnosis. Contributions from leading experts provide a comprehensive overview of healthcare for HBOPPC patients, including reproductive medicine and perinatal care, while addressing critical questions about individualized risk management and genetic counseling.
This book is an essential resource for breast surgeons and oncologists, obstetricians, gynecologists, pancreatic cancer surgeons, urologists, and genetic medicine physicians. It also serves as a valuable reference for HBOC patients, their families, and pharmaceutical professionals involved in PARP inhibitor development. By sharing the latest research and clinical practices, this volume aims to equalize and enhance HBOPPC treatment across Japan.
Offers comprehensive insights into the molecular mechanisms of carcinogenesis and the role of BRCA1/2 mutations Includes data on nationwide registration, expert insights, and key discussions on clinical and healthcare developments Covers BRCA1/2 mutation impacts and risk-reducing surgery
Autor*in
Takanori Ishida
Themen in »Practical Guide to Hereditary Breast and Ovarian Cancer V«
HBOC Hereditary Breast and Ovarian Cancer BRCA1 BRCA2 BRCA1/2 variants Reproductive medicine Perinatal medicine Pancreatic cancer Prostate cancer Genetic testing Surveillance PARP inhibitors Risk reducing surgery