In Silico Engineering of Disulphide Bonds to Produce Stable Cellulase

Beschreibung

This Brief highlights different approaches used to create stable cellulase and its use in different fields. Cellulase is an industrial enzyme with a broad range of significant applications in biofuel production and cellulosic waste management. Cellulase 7a from Trichoderma reesei is the most efficient enzyme in the biohydrolysis of cellulose. In order to improve its thermal stability, it can be engineered using a variety of approaches, such as hydrophobic interactions, aromatic interactions, hydrogen bonds, ion pairs and disulfide bridge creation.

This Brief highlights different approaches used to create stable cellulase and its use in different fields. Cellulase is an industrial enzyme with a broad range of significant applications in biofuel production and cellulosic waste management. Cellulase 7a from Trichoderma reesei is the most efficient enzyme in the bio hydrolysis of cellulose. In order to improve its thermal stability, it can be engineered using a variety of approaches, such as hydrophobic interactions, aromatic interactions, hydrogen bonds, ion pairs and disulfide bridge creation.

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Bahram Barati

Themen in »In Silico Engineering of Disulphide Bonds to Produce Stable Cellulase«

Biofuel Production Biohydrolysis of Cellolose Disulphide Bonds to Cellulase GROMACS Software Industrial Enzyme Molecular Dynamic Simulation Trichoderma Reesei biochemical engineering

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