Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis.This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective.The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cellmediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained.The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy.The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers.The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
New insight into etiopathogenesis of Immunological factor in Recurrent Miscarriages & Implantation Failure, helping to understand the subject better
Complete overview of Immunotherapy currently practised globally.
Includes Diagnostic work up for immunological factor, that will help clinicians in their practice
The book compehensively covers about various modalities of Immunotherapy in RM/IF. No single book is available covering all that.
Discusses etiopathogenesis of Immunological factor in Recurrent Miscarriages & Implantation Failure Provides an overview of Immunotherapy in Recurrent Pregnancy Loss Covers various modalities of Immunotherapy in RM/IF
Mohan Raut
Immunotherapy Lymphocyte Immunization Therapy (LIT) Recurrent Miscarriages Implantation Failure Unexplained Infertility Reproductive Immunology