The 'Big Four’ Snakes of India
Venom Composition, Pharmacological Properties and Treatment of Envenomation
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Beschreibung
This book provides detailed and updated knowledge about medically important ‘Big Four’ venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russell’s viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing ‘Big Four’ venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of ‘Big Four’ venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom,prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient.
This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms.
This book provides detailed and updated knowledge about medically important ‘Big Four’ venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russell’s viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing ‘Big Four’ venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of ‘Big Four’ venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom,prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient.
This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms.
Describes Biochemical composition, pharmacological properties of Big Four snake venoms and their pathophysiological and clinical manifestations in snakebite patients Describes proteomic approach to decipher the venom proteome composition of Big Four venomous snakes of India Provide details about production of commercial anti-snake venom, treatment of snakebite, and limitations of antivenom therapy Enlists candidate drug prototypes from Indian snake venom some of which have market demand for the treatment of various diseases such as cancer, cardiovascular diseases, and wound healing
Autor*in
Ashis K. Mukherjee
Themen in »The 'Big Four’ Snakes of India«
toxinology Indian cobra venom Indian common krait venom Indian Russell’s viper venom Indian saw-scaled viper venom Proteomic analysis of Indian snake venom Snakebite treatment