Multiple Action-Based Design Approaches to Antibacterials

Beschreibung

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development. 

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development. 

Provides readers with suggestions for further research using specific examples as starting points in the design process – for example, the antibacterial alkaloid berberine Includes a comparative section relating combinations, hybrids, and pro-drug features which will assist further developments in the field Suggests for pathways to refine some illustrative hypothetical molecular examples in order to bring them closer to experimental testing

Autor*in

John Bremner

Themen in »Multiple Action-Based Design Approaches to Antibacterials«

Antibacterials Drugs Drug Combinations Prodrugs Multiply Active Antibacterials Molecular Design Drug Design Single Molecule Hybrids Drug Development Alkaloid Berberine Medicinal Chemistry Design

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