UHMWPE Biomaterials for Joint Implants
Structures, Properties and Clinical Performance
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Beschreibung
This book presents a comprehensive, state-of-the-art review of the latest progresses in UHMWPE biomaterials, which has been critical for the performance and longevity of joint implants. Oriented by clinical challenges to UHMWPE-based joint implants, it introduces the processing, crosslinking, structural manipulation, oxidation mechanism, stabilization, drug delivery, and wear, as well as clinical performance, biomechanics, and simulated studies of joint implant based on UHMWPE with low wear, which are aimed to tackle or minimize the adverse effect related to wear and wear debris. These contributions provide fundamentals of chemistry and physics of UHMWPEs to help understand the clinical performances of UHMWPE based joint implants. Perspectives to next generation UHMWPE to meet the unmet challenges in clinical use are included.
This book presents a comprehensive, state-of-the-art review of the latest progresses in UHMWPE biomaterials, which has been critical for the performance and longevity of joint implants. Oriented by clinical challenges to UHMWPE-based joint implants, it introduces the processing, crosslinking, structural manipulation, oxidation mechanism, stabilization, drug delivery, and wear, as well as clinical performance, biomechanics, and simulated studies of joint implant based on UHMWPE with low wear, which are aimed to tackle or minimize the adverse effect related to wear and wear debris. These contributions provide fundamentals of chemistry and physics of UHMWPEs to help understand the clinical performances of UHMWPE based joint implants. Perspectives to next generation UHMWPE to meet the unmet challenges in clinical use are included.
Covers the fundamentals of the chemistry, structure, mechanical performance, crosslinking, and wear of UHMWPE and their significance for clinical applications Timely reviews the latest progresses in both UHMWPE biomaterials and clinical outcome of recently approved UHMWPE biomaterials Presents a new idea to minimize the biological response to wear debris through a drug delivery strategy Helps biomedical engineers and implant professionals to better understand the future opportunities of UHMWPE biomaterials
Autor*in
Jun Fu
Themen in »UHMWPE Biomaterials for Joint Implants«
Radiation crosslinking Antioxidants Stabilization of crosslinked UHMWPE Clinical performance Mechanical properties Wear resistance Lipid-induced oxidation UHMWPE-based joint implants