Protein-Protein and Domain-Domain Interactions
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Beschreibung
This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions. The significance of such complex formation in human biology in the light of molecular evolution is also highlighted using several examples. The chapters also describe recent advancements on the molecular principles of protein-protein interaction with reference to evolution towards target identification in drug discovery. Finally, the book also elucidatesa comprehensive yet a representative description of a large number of challenges associated with the molecular interaction of proteins.
- This is the first book to combine Protein-Protein interactions with domain-domain interactions explaining the mechanism of gene fusion with appropriate hypothesis.
-This book provides a comprehensive overview of advanced topics in Bioinformatics
-This book explains complex concepts on the subject using simple graphical illustrations
-Each chapter will contain 20 exercise problems or questions for practice
-It provides a descriptive understanding of molecular regulation towards vaccine development and disease-specific target discovery
This is the first book to combine Protein-Protein interactions with domain-domain interactions explaining the mechanism of gene fusion with appropriate hypothesis This book provides a comprehensive overview of advanced topics in Bioinformatics This book explains complex concepts on the subject using simple graphical illustrations Each chapter will contain 20 exercise problems or questions for practice It provides a descriptive understanding of molecular regulation towards vaccine development and disease-specific target discovery
Autor*in
Pandjassarame Kangueane
Themen in »Protein-Protein and Domain-Domain Interactions«
Protein-protein interactions domain-domain interactions gene fusion Protein complexes Drug discovery Vaccine development vaccines