Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobotics
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Beschreibung
This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.
Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015
Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule activities
Explores the biomedical applications of atomic force microscopy (AFM) in clinical practice for targeted cancer therapy
Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015 Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule activities Explores the biomedical applications of atomic force microscopy (AFM) in clinical practice for targeted cancer therapy Includes supplementary material: sn.pub/extras
Autor*in
Mi Li
Themen in »Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobotics«
Atomic Force Microscopy AFM Lymphoma targeted therapy Cell mechanics Single-molecule force spectroscopy single-cell activities single-molecule activities nanoscale robot Biological Microscopy