This book highlights recent advances in and diverse techniques for exploring the plasma membrane’s structure and function. It starts with two chapters reviewing the history of membrane research and listing recent advances regarding membrane structure, such as the semi-mosaic model for red blood cell membranes and the protein layer-lipid-protein island model for nucleated tissue cell membranes. It subsequently focuses on the localization and interactions of membrane components, dynamic processes of membrane transport and transmembrane signal transduction. Classic and cutting-edge techniques (e.g. high-resolution atomic force microscopy and super-resolution fluorescence microscopy) used in biophysics and chemistry are presented in a very comprehensive manner, making them useful and accessible to both researchers in the field and novices studying cell membranes. This book provides readers a deeper understanding of the plasma membrane’s organization at the single molecule level and opens a new way to reveal the relationship between the membrane’s structure and functions, making it essential reading for researchers in various fields.
Presents recent advances in understanding membrane structure and functions
Includes classic and cutting-edge techniques for exploring and analyzing membrane composition
Describes essential protocols for the study of membranes
Ideal for experienced researchers in the field and newcomers alike
Hongda Wang
Membrane structure Atomic force microscopy Single molecule force spectroscopy Super-resolution fluorescence microscopy Single molecule fluorescence Electron microscopy Cryo-electron microscopy NMR spectroscopy Infrared and raman spectrum Computer simulation