Understanding Depression

Beschreibung

This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological issues. Detailed information is presented on a wide range of topics, including genetics, molecular and cellular biology, and aspects at the neural circuit and multicellular system levels. Readers will gain a deeper appreciation of the factors and interactions underlying individual variation in responsiveness to stress and vulnerability to depression, as well as a clear understanding of potential treatment targets and causes of treatment resistance based on the latest research. A concluding section considers progress towards precision psychiatry and gender and cultural differences in depression. Thecompanion volume is dedicated to clinical and management issues in depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.

Equips readers with an up-to-date understanding of the biomedical and neurobiological underpinnings of depression

Elucidates the factors and interactions underlying individual variation in vulnerability to depression

Identifies potential treatment targets and causes of treatment resistance

Autor*in

Yong-Ku Kim

Themen in »Understanding Depression«

Pharmacogenetics Imaging genetics Early life stress Seretonin receptors Glutamate receptors mTOR pathway Cellular aging Biological markers Neuroimaging Cortical-subcortical interactions Novel drug discovery Personalized clinical approach Gender differences Epidemiology of major depressive disorder

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