In silico Modeling and Experimental Validation for Improving Methanogenesis from CO2 via M. maripaludis

Beschreibung

This thesis explores the ability of M. maripaludis to capture and convert CO2 to methane in the presence of free nitrogen, and offers a consolidated review of the metabolic processes and applications of M. maripaludis. Further, it develops, validates and analyzes the first genome-scale metabolic model (iMM518) of M. maripaludis. Readers will discover, for the first time, the impact of nitrogen fixation on methane production. As such, the thesis will be of interest to researchers working on M. maripaludis, biofuels and bioenergy, systems biology modeling and its experimental validation, estimation of maintenance energy parameters, nitrogen fixing microbes, and bioremediation.
This thesis explores the ability of M. maripaludis to capture and convert CO2 to methane in the presence of free nitrogen, and offers a consolidated review of the metabolic processes and applications of M. maripaludis. Further, it develops, validates and analyzes the first genome-scale metabolic model (iMM518) of M. maripaludis. Readers will discover, for the first time, the impact of nitrogen fixation on methane production. As such, the thesis will be of interest to researchers working on M. maripaludis, biofuels and bioenergy, systems biology modeling and its experimental validation, estimation of maintenance energy parameters, nitrogen fixing microbes, and bioremediation.
Provides an original and comprehensive view on the metabolic process of M. maripaludis Develops the first genome-scale metabolic model, iMM518, of M. maripaludis, to quantify the metabolic fluxes during in genetic and environmental perturbations The first book to examine the impact of diazotrophy on methane production Winner of the National University of Singapore’s President Graduate Fellowship (PGF) Includes supplementary material: sn.pub/extras

Autor*in

Nishu Goyal

Themen in »In silico Modeling and Experimental Validation for Improving Methanogenesis from CO2 via M. maripaludis«

Methanococcus maripaludis Genome-Scale Modeling Flux Measurements Maintenance Energy Carbon Dioxide Methanogenesis M. maripaludis Diazotrophy Carbon Capture Carbon Conversion Microbial Electrolysis Cells (MECs) Electromethanogenesis biochemical engineering systems biology

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