Modelling Protocells
The Emergent Synchronization of Reproduction and Molecular Replication
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Beschreibung
The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that selection may take place. Sustainable protocell populations have not yet been obtained experimentally and mathematical models are therefore extremely important to address key questions concerning their synthesis and behavior. Different protocell “architectures” have been proposed and high-level abstract models like those that are presented in this book are particularly relevant to gain a better understanding of the different properites. These models are able to treat all the major dynamical phenomena in a unified framework, so they can be seen as “virtual laboratories” for protocell research. Particular attention is paid to the problem of synchronization of the fission rate of the whole protocell and the duplication rate of its "protogenetic" material, which is shown to be an emergent property that spontaneously develops in successive generations.
The book is of interest for a broad range of scientists working in soft matter physics, chemistry and biology, interested in the role protocells may play on the development of new technologies with medical, environmental and industrial applications as well as scientists interested in the origin of life.
Provides a unitary approach to protocell models
Includes a brief discussion on the role of quantum coherent states in the origin of life
Written by the Chairman of the Science Board of the European Centre for Living Technology
Provides a unitary approach to protocell models Includes a brief discussion on the role of quantum coherent states in the origin of life Written by the Chairman of the Science Board of the European Centre for Living Technology Includes supplementary material: sn.pub/extras
Autor*in
Roberto Serra
Themen in »Modelling Protocells«
Autocatalytic Set Cell Evolution Emergent Properties Genetic Memory Internal Reaction Models Lipid Vesicles Models of Replicators Dynamics Origins of Life Protocell Architectures Surface Reaction Models RAF sets Reflexive Autocatalytic Food-Generated sets Kauffman random topologies synchronization autocatalytic cycle