Aminoacyl-tRNA Synthetases in Biology and Medicine
Buch in deiner Nähe kaufen
Beschreibung
1 Synthetic and Editing Mechanisms of Aminoacyl-tRNA Synthetases
John J. Perona, Ita Gruic-Sovulj
2 Emergence and Evolution
Tammy J. Bullwinkle, Michael Ibba
3 Architecture and Metamorphosis
Min Guo, Xiang-Lei Yang
4 Protein–Protein Interactions and Multi-component Complexes of Aminoacyl-tRNA Synthetases
Jong Hyun Kim, Jung Min Han, Sunghoon Kim
5 Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell–Cell Communication
Sung Hwa Son, Min Chul Park, and Sunghoon Kim
6. Non-catalytic Regulation of Gene Expression by Aminoacyl-tRNA Synthetases
Peng Yao, Kiran Poruri, Susan A. Martinis, Paul L. Fox
7 Amino-Acyl tRNA Synthetases Generate Dinucleotide Polyphosphates as Second Messengers: Functional Implications
Sagi Tshori, Ehud Razin, Hovav Nechushtan
8 Association of Aminoacyl-tRNA Synthetases with Cancer
Doyeun Kim, Nam Hoon Kwon, Sunghoon Kim
9 Pathogenic Implications of Human Mitochondrial Aminoacyl-tRNA Synthetases
Hagen Schwenzer, Joffrey Zoll, Catherine Florentz, Marie Sissler
10 Role of Aminoacyl-tRNA Synthetases in Infectious Diseases and Targets for Therapeutic Development
Varun Dewan, John Reader, Karin-Musier Forsyth
11 Flexizymes, Their Evolutionary History and Diverse Utilities
Toby Passioura, Hiroaki Suga
This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
Will attract broad readership from basic life science to biotechnology and medical community Describes how aminoacyl-tRNA synthetases give insight into the emergence and evolution of life Shows how the function of a gene can be diversified at protein level Describes how a central metabolism such as protein synthesis is coordinated with other cellular processes Covers ARS-related pathologies and novel activities, which provide new understanding of human diseases and therapeutic opportunities Written by leading experts in the field
Autor*in
Sunghoon Kim
Themen in »Aminoacyl-tRNA Synthetases in Biology and Medicine«
Aminoacyl-tRNA Synthetases Reviewed Immune Diseases Multicomponent Complexes Neural Diseases Novel functions of tRNAs Protein Interactions Reprogramming of Genetic Code Synthetic Bio-Medicine systems biology