Coronary Pressure
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Beschreibung
Cardiologists must answer three important questions when evaluating and treating patients with a coronary artery stenosis. As a physiologist: "What is the effect of this stenosis on coronary blood flow and myocardial function?"; as a clinician: " Is this lesion responsible for the patient's symptoms?"; and finally as an interventionalist: "Will revascularization of this artery improve the patient?" Fundamentally, the answer to these questions can be given to a large extent by measuring coronary pressure. That is the rationale of writing this book. 1. 1 Historical overview. Andreas Gruentzig and most interventional cardiologists in the early days of PTCA, had the intuitive feeling that pressure measurements could help to establish the severity of a coronary stenosis and to monitor the progress and result of a coronary intervention. At that time, measuring coronary pressure by the balloon catheter was part of a standard procedure. A residual transstenotic gradient of less than 15 mmHg was generally considered as a good result. Later, however, it turned out that measuring these (resting) gradients with balloon catheters was inaccurate an only had a limited prognostic value. Moreover, because there was no consistent theory to correlate pressure measurements to blood flow, the interest in measuring coronary pressures faded and disappeared almost completely with the introduction of new balloon catheters not intended for pressure measurement.
Autor*in
N.H. Pijls
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`It has been the enormous contribution of Drs. Pijls and De Bruyne and their colleagues that they have been able to develop such an approach, that has been further improved, extensively validated and applied in routine practice. ... This book has been written such that both the practical cardiologist who wants to know how to perform the procedure according to the rules, as well as the scientist who wants to know everything about the underlying principles and the results of the validation studies, will find it very useful. In conclusion, this book is a must for the practicing interventionalist as well as the scientist who is interested in coronary and myocardial physiology. The two authors are to be congratulated on writing such a nice and innovative piece of work.'
International Journal of Cardiac Imaging, 14 (1998)
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