Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms
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Beschreibung
This work is focused on different aspects within the loop of multiscale modeling:
On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.
On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.
On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
This work is focused on different aspects within the loop of multiscale modeling: On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated. On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed. On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
Autor*in
David Urs Josef Keller
Themen in »Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms«
Multiscale Modeling Forward Calculation Cardiac Electrophysiology Electrophysiological Heterogeneities