Vergleichende Untersuchungen zur Wirkung von Bentonit bei Durchfallerkrankungen von Hunden
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Beschreibung
Comparative studies on the effect of bentonite in diarrhea in dogs
The aim of this study is to evaluate the efficacy of bentonite as a concomitant agent in the therapy of acute diarrhea in dogs. Bentonite was applied to a control group at concentrations of 1.25, 2 and 5 percent of the dry matter (DM). This study included 137 dogs of different breeds, including mixed breeds. Grouping was carried according to the age, body weight, sex and intactness. Concentrations to be in the dry matter were determined prior to the study in an in-vitro trial. Evaluation criteria for the efficacy of bentonite were duration of diarrhea, color of the stool, fecal consistency, frequency of defecation and defined blood parameters. The trial period lasted seven days, during which blood samples were taken from day 1 to 4 plus a final sampling on day eleven. Over this period, the tendency, difference and course of blood parameters were investigated. Additionally bentonite concentrations were compared to those in commercially available preparations.
In the present study, bentonite showed a dosage-dependent positive impact on duration of disease, consistency of the feces and on the outcome of treatment of diarrhea. Regarding blood parameters, no significant influence was observed as they remained within their physio-logical range. However bentonite seems to have a stabilizing effect on the values of Iron, Cal-cium and Potassium compared to the control group. Furthermore, the group with the highest dosage (5 percent of DM) showed an increase of white blood cell number and corresponding liver enzymes. This phenomenon could still be observed after ending the treatment. Dosages of 2.5 and 5 percent of dry matter respectively showed an overall positive influence on diar-rhea index whereas a dosage of 1.25 percent seemed to have a negative effect on the success-ful treatment of acute diarrhea. Nonetheless regarding all evaluated criteria together the low-est dosage (1.25 percent of DM) had the highest efficacy.
In conclusion, this study showed bentonite to be a useful adjuvant in the treatment of mild diarrhea without clinically observable dehydration. Dosages should be at 2.5 or 5 percent of DM or range in between. Evaluation of blood parameters on day eleven showed that high dosages of bentonite (>5 percent DM) cause stress to the liver and therefore should be avoid-ed. It is strongly advisable not to exceed a duration of treatment of seven days even at dosages within the mentioned range.
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Dirk Oschika
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Blutbild Durchfall Hunde Kot antidiarrhoea agents bentonite blood picture diarrhoea diarrhoea dogs faeces leukocytes