Rational engineering of the methylerythritol 4-phosphate (MEP) pathway for terpenoid production through metabolic control analysis

Beschreibung

Terpenoids include high value chemicals such as pharmaceuticals, chemical precursors and fine chemicals. Fruthermore, terpenoids are of interest as environmental-friendly replacement of fossil derivate chemicals. Here, the 2 C methyl D erythritol 4 phosphate (MEP) pathway was analyzed in Escherichia coli through metabolic control analysis for production of the model terpenoid isoprene. Several limiting steps were identified and their implication for an efficient pathway design is discussed.

Autor*in

Daniel Volke

Themen in »Rational engineering of the methylerythritol 4-phosphate (MEP) pathway for terpenoid production through metabolic control analysis«

Synthetische Biologie Metabolic engineering

Stimmen zu »Rational engineering of the methylerythritol 4-phosphate (MEP) pathway for terpenoid production through metabolic control analysis«

Details

Link teilen