Microarrays in Inflammation
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Beschreibung
The book is of interest to academic and industrial researchers but also clinicians who are working on inflammation related topics and would like to extend their knowledge about microarrays and the application thereof. After reading the book a researcher or clinician should be in the position to plan, perform and analyse or to critically review microarray experiments related to inflammation research.
So far, non of the published books covers all aspects which need to be taken into account when planning and performing a microrray experiment in inflammation research. Normally, for a researcher or clinician doing a microarray experiment it is not enough to have knowledge about microarrays , as the experiment does not start with purified and quality controlled RNA and does not end with signal intensities. Things like appropriate cell sorting techniques, stabilisation and transport of RNA or cells, the knowledge how to deal with whole blood as well as options for automation are crucial for a successful application of microarrays. Moreover these aspects are the main obstacles for transferring microarray based inflammation analysis from bench to bedside and the limiting factors for higher through put as needed in multicenter studies.
Summarizes the most advanced technical aspects from sample generation to data analysis Presents successful applications of microarrays in major fields of inflammation research Helps to plan, perform and analyse microarray experiments
Autor*in
Andreas Bosio
Themen in »Microarrays in Inflammation«
Expression PCR Polymerasekettenreaktion RNA asthma blood cell gene gene expression genes inflammation lymphoma microarray research tissue