Several compounds are associated with experimentally induced neoplasms in the urinary systems, and especially the kidneys, of laboratory animals. Many of these neoplasms are succintly described and illustrated in detail in this volume, and some are compared with spontaneously occurring lesions. Pragmatic aspects of disease which are of particular interest to pathologists are emphasized, such as classification and differential diagnosis of neoplasms that occur in the urinary system; comparison and significance of toxic effects of substances in animals and humans; and similarities and differences in disease manifestations between animals and humans.
Includes standardized nomenclature - Facilitates uniform interpretation of bioassay results worldwide - Electron micrographs in exquisite detail illustrate results of recent research - Provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures
Many toxins cause significant changes in the kidneys of laboratory animals and humans and are of interest to toxicologic pathologists. This group of toxic substances are considered in detail, particularly in reference to the specific structures of the kidney affected.
Thomas C. Jones
analgesics calcium cancer carcinogenesis carcinoma cell classification histology infection kidney pathogenesis research tissue toxicity tumor