Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.
Includes supplementary material: sn.pub/extras
Gisou van der Goot
Bacterial protein toxins aerolysin bacteria biology cell cell intoxication cytolysins helicobacter pylori membrane pore-forming colicins protein proteins receptor toxin virulence