Leontis RNA 3D Structure Analysis and Prediction

RNA 3D Structure Analysis and Prediction

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Beschreibung

With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.


With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.


First book on RNA 3D structure prediction based on sequence data alone Gives a comprehensive overview on the current status and progress in the field Covers a variety of RNA prediction methods Includes supplementary material: sn.pub/extras

Autor*in

Neocles Leontis

Themen in »RNA 3D Structure Analysis and Prediction«

3D Modelling RNA RNA analysis RNA prediction RNA structure

Stimmen zu »RNA 3D Structure Analysis and Prediction«

Details

ISBN: 9783642445699
Verlag: Springer Berlin
Erscheinung: 11.06.2014

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