Neutron Capture Therapy
Principles and Applications
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Beschreibung
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter. This in principle allows for tumor cell-selective high-LET particle radiotherapy. NCT is exciting scientifically but challenging clinically, and a key factor in success is close collaboration among very different disciplines.
This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.
State of the art report on neutron capture therapy Summarizes the progress made in recent decades Multidisciplinary approach Written by the most experienced specialists Includes supplementary material: sn.pub/extras Includes supplementary material: sn.pub/extras
Autor*in
Wolfgang A.G. Sauerwein
Themen in »Neutron Capture Therapy«
Boron Neutron Capture Therapy (NCT) Particle Therapy Radiation Oncology Targeted Therapies Radiaton Oncology
Stimmen zu »Neutron Capture Therapy«
From the reviews:
“This book examines the principles and applications of neutron capture, a largely promising but as yet unproven radiotherapy. … Clinicians who have an active interest in neutron capture therapy are the intended audience.” (James G. Douglas, Doody’s Book Reviews, January, 2014)
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