Drug Design
Methodology, Concepts, and Mode-of-Action
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Beschreibung
This unique and comprehensive work on structure-based drug design clarifies the spatial relationships between interacting molecules, and features a raft of applications and methods. The electronic version includes computer animations of 3D structures.
Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.
Unique reference work on the subject of drug design
Full colours throughout
Intelligibly written and illustrated containing over 100 computer graphics
Including an index of about 5,000 items
Autor*in
Gerhard Klebe
Themen in »Drug Design«
Drug Design Hit-to-lead optimization Screening technologies computer methods and modelling drug targets, mode-of-action
Stimmen zu »Drug Design«
Aus den Rezensionen:
“... stellt eine sehr gute Informationsquelle für einen Diplomanden oder Doktoranden der pharmazeutischen Chemie dar, der in diesem Bereich arbeitet und am Beginn seiner wissenschaftlichen Karriere steht ... für jeden Lehrenden in der pharmazeutischen Chemie geeignet, um die Vorlesung um interessante Aspekte zu ergänzen.“ (Dr. Stefan Fischer, in: MMP Medizinische Monatsschrift für Pharmazeuten, Heft 6, 2014)
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