Drug Design

Beschreibung

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.
Unique reference work on the subject of drug design Full colours throughout Intelligibly written and illustrated containing over 100 computer graphics Including an index of about 5,000 items

Autor*in

Gerhard Klebe

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Drug Design Hit-to-lead optimization Screening technologies computer methods and modelling drug targets, mode-of-action

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