This book is about the cellular mechanisms evolved by human beings to protect their genetic materials from genotoxic damage, and its numerous pathological consequences, including cancer and hereditary diseases. The various DNA repair pathways are part of a much larger picture of intracellular metabolisms, which includes gene expression, chromosome duplication, signal transduction, cell cycling, genomic evolution, genetic mobility, and cell death. The major thrust of this volume is on our growing understanding of human diseases through the study of DNA repair. It aims at stimulating new areas of research in the future usage of DNA repair mechanisms for the treatment of human diseases.
Jean-Michel H. Vos
DNA DNA repair DNA repair capacity (DRC) VDJ recombination apoptosis cancer cell cell death chromosome gene expression genome metabolism nucleotide oxcision repair programmed cell death signal transduction
"If you are a clinician...you would be purchasing wisely if you bought this book. if you are a research professional...there is really no excuse not to get one for your lab. If you are a student and want an A+ ...buy one or borrow your supervisors copy." Cancer Forum
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