Growth Hormone, Prolactin and IGF-I as Lymphohemopoietic Cytokines
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Beschreibung
This book describes three growth and differentiation factors and their role in basic and clinical hematology and immunology: growth hormone, insulin-like growth factor 1 and prolactin. Recently, the expression of all three factors has been documented in the lympho-hemopoietic system. The relative importance of endocrine, paracrine and autocrine production is discussed. In addition to their role in development and physiology, these factors are implicated in auto-immune diseases and leukemia. Possible implications of recent findings include the use of these factors in some forms of bone-marrow aplasia and immunodeficiency. In contrast, bromocriptine (which suppresses PRL secretion) may be of value in auto-immune diseases.
Autor*in
Elizabeth L. Hooghe-Peters
Themen in »Growth Hormone, Prolactin and IGF-I as Lymphohemopoietic Cytokines«
Auto-immune disease Gowth Hormone IGF-1 Immunology Insulin-like growth factor Prolactin