Chimerism and Tolerance
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Beschreibung
Chimerism, the co-existence of two or more genetically distinct components within one organism, has existed as a concept for centuries. However, the recognition that bone marrow chimerism confers tolerance for transplanted donor tissues, has occurred only during this century. Bone marrow is the only transplantable graft that is permanently accepted without requirement for antirejection agents to prevent graft rejection. This book is about the various types of tolerance which have been observed in association with chimerism and the mechanism by which this unique process may occur. Contributions from world-recognized experts in the field review the clinical as well as basic science aspects of chimerism and tolerance.
Autor*in
Suzanne T. Ildstad
Themen in »Chimerism and Tolerance«
immunology transplant immunology transplantation