Thermodynamics and Kinetics of Drug Binding
Buch in deiner Nähe kaufen
Beschreibung
This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.
Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.
Autor*in
György M. Keserü
Themen in »Thermodynamics and Kinetics of Drug Binding«
Chemie Chemistry Drug Discovery & Development Enzyme u. Rezeptoren Enzymes & Receptors Physical Chemistry Physikalische Chemie Rezeptor Wirkstoffforschung Wirkstoffforschung u. -entwicklung