Chemogenomics in Drug Discovery
A Medicinal Chemistry Perspective
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Beschreibung
Die Chemogenomik ist eine Brückendisziplin zwischen Chemie und Biologie, die im Rahmen der Suche nach neuen Wirkstoffen Ansätze der kombinatorischen Chemie mit Proteomik und Genomik verbindet. Zwanzig Forschungsgruppen von Universitäten und aus pharmazeutischen Unternehmen erläutern Ihnen in diesem Band alle Schritte der frühen Wirkstoffforschung - von der Wahl des Targets über Verbindungsbibliotheken bis zum Design von Leitstrukturen. Wirkstoffentwickler und medizinische Chemiker, die mit chemogenomischen Methoden arbeiten, werden auf diese umfangreiche und kompetente Informationsquelle nicht verzichten wollen.
Autor*in
Hugo Kubinyi
Themen in »Chemogenomics in Drug Discovery«
Biowissenschaften Cell & Molecular Biology Chemical Informatics Chemie Cheminformatik Chemistry Computational chemistry Drug Discovery & Development Genomforschung u. Proteomik Genomics & Proteomics Life Sciences Medizinische Chemie Molekularbiologie Organische Chemie Wirkstoffforschung u. -entwicklung
Stimmen zu »Chemogenomics in Drug Discovery«
"In summary, this book provides up-to-date insights into the world of chemogenomics. Most chapters are of excellent quality, providing numerous and diverse contributions from industrial practice. "Chemogenomics in Drug Discovery" offers a practical definition of chemogenomics in order to foster a clear understanding of this genome-wide drug-discovery approach. The book is valuable for graduate students anf for academic and industrial researchers who want to learn about modern drug-discovery approaches."CHEMBIOCHEM - A European Journal of Chemical Biology "The contributions in >Chemogenomics in Drug Discovery< are of very high quality and are clearly presented ... All chapters have a high scientific value, and collectively they contribute a great deal to the understanding of how chemogenomics and scaled-up medicinal chemistry can support the early stages of drug discovery. Therefore, this work is highly relevant for everyone with an intereste in modern drug development, and especially for readers in the pharmaceutical industry."Ulf Börjesson, Institute of Pharmaceutical Chemistry, University of Marburg, Angewandte Chemie, IE, 3rd May Issue 2005-44/19+ Angewandte Chemie, 3. Maiheft 2005-117/19 "... readers hoping to learn about specific aspects will be rewarded with superb writing, good discussions, and excellent examples from current literature."Steven M. Firestine, Division of Pharmaceutical Sciences, Mylan School of Pharmacy, Duquesne University, Pittsburgh, Journal of Medicinal Chemistry, Vol. 48, No. 11/2005 "This hallmark text marks a breakthrough in the field...vital to the researcher."Electric Review, April/May 2005
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