Analogue-based Drug Discovery
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Beschreibung
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds.
Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.
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Themen in »Analogue-based Drug Discovery«
Analogwirkstoff Arzneimittel Chemie Chemistry Drug Discovery & Development Molecular Pharmacology Molekulare Pharmakologie Natural Products Naturstoffchemie Pharmazeutische Chemie Wirkstoff Wirkstoffforschung u. -entwicklung
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"This book is eminently capable of educating both newcomers and experienced practitioners to the fields of medicinal chemistry and pharmacology, and it is highly recommended as an addition to the personal collection of the practicing drug designer and as a reference volume for institutional use as well."
Journal of Medicinal Chemistry
"Overall the book is of interest for medicinal chemists who already have a sound knowledge of aspects of analogue-based drug design." ChemMedChem
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