The Aptamer Handbook

Beschreibung

In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes).
Basic concepts and technologies describing in detail how these functional oligonucleotides can be identified are presented. Numerous examples demonstrate the versatility of in vitro selected oligonucleotides. Special emphasis has been put on a section that shows the broad applicability of aptamers, e. g. in target validation, for analytics, or as new therapeutics.
This first overview in the field is of prime interest for a broad audience of scientists both in academia and in industry who wish to expand their knowledge on the potential of new oligonucleotide functions and their applications.

Autor*in

Sven Klussmann

Themen in »The Aptamer Handbook«

Biochemie Biomolecules (DNA, RNA, Peptides, etc.) Biomoleküle (DNA, RNA, Peptide) Biotechnologie Biotechnologie i. d. Biowissenschaften Biotechnology Biowissenschaften Chemie Chemistry Life Sciences Medizinische Chemie Molekularbiologie Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie

Stimmen zu »The Aptamer Handbook«

"Considering the overall effort by the editor to gather work by some of the leading researchers on aptamers, I believe The Aptamer Handbook will be referred to as an encyclopedia on aptamer research. This book would most likely appeal to someone who has interest in combinatorial libraries, nucleic acids, and biosensors. Therefore, it would be an excellent addition to the libraries of universities, institutes, and industry, given the diverse aptamer applications in various fields." ChemBioChem
 
"Overall, this is an outstanding book and it will deservedly become the resource of choice for the growing legion of researchers in the aptamer field. Clear illustrations, extensive reference lists for each chapter, and a detailed index supplement the excellent writing. Students and faculty members at all levels will benefit from reading selected chapters in isolation, or from methodically reading the entire book."
Angewandte Chemie

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"Insgesamt gesehen ist das Buch...hervorragend. Für Forscher auf dem Gebiet der Aptamere wird es mit Recht zu dem Nachschlagewerk avancieren. Klare Abbildungen, eine ausführliche Liste mit Literaturhinweisen in jedem Kapitel und ein detailliertes Sachwortverzeichnis ergänzen die ausgezeichnete Darstellung der Themen. Studierende wie auch fortgeschrittene Wissenschaftler werden von der Lektüre profitieren."
Angewandte Chemie
 

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