Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection
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Beschreibung
According to the World Health Organization, approximately one third of the world’s population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection.
TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition.
This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host’s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarettesmoking and aging, and strategies to restore favorable immune responses against this deadly pathogen.
Editor and contributors are internationally recognized experts in TB research
Discusses the latest findings on comorbidity between TB and various conditions
Novel focus on the effects of chronic smoking and ageing on immune response against TB
Editor and contributors are internationally recognized experts in TB research Discusses the latest findings on comorbidity between TB and various conditions Novel focus on the effects of chronic smoking and ageing on immune response against TB
Autor*in
Vishwanath Venketaraman
Themen in »Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection«
HIV infected individuals chronic smokers diabetes tuberculosis mycobacterium extrapulmonary pulmonary infectious diseases