Neural Functions of the Delta-Opioid Receptor

Beschreibung

This is the first book to summarize the progress of research on the delta opioid receptor (DOR) to date. This receptor, a member of the opioid receptor family, was not studied at all until the 1990s when some researchers began looking into the role that it plays in neuroprotection and other functions. Many scientists from a number of independent labs have now confirmed that DOR can provide neuroprotection from hypoxic/ischemic injuries. They have also found that it plays a role in physiological and pathophysiological events such as hypoxic encephalopathy, epilepsy, acupuncture, Parkinson's disease, etc. by regulating membrane proteins and balancing intracellular survival/death signals. The book provides a comprehensive overview of the current state of research and provide a blueprint for future directions.
This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. This receptor, a member of the opioid receptor family, was traditionally thought to be primarily involved in pain modulation. Recent new findings have shown its unique role in neuroprotection and many other functions. Many scientists from a number of independent laboratories have now confirmed that DOR can provide neuroprotection against hypoxic/ischemic injuries. They have also found that it plays a role in a variety of physiological and pathophysiological events such as hypoxic encephalopathy, epilepsy, acupuncture, Parkinson's disease, etc. by regulating ionic homeostasis, glutamate transportation and signaling, and balancing intracellular survival/death signals. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.
The first book to provide a comprehensive overview on neural functions of the Delta Opioid Receptor Includes contributions from major DOR researchers in the world Covers the topic from cellular aspects to clinical potentials?

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Ying Xia

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delta opioid receptor hypoxic/ischemic injury neuroprotection opioid receptors neurogenesis

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“Recent development in research dedicated to the function of δ-opioid receptors (DORs) is reviewed in this book. … Book may serve for graduated as well as undergraduated students who wish to get better insight into topics covered by individual chapters. It will be indispensable reference book for scientists working on any aspect of opioid research.” (Lubica Lacinova, General Physiology and Biophysics, Vol. 35 (4), 2016)

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