The Discreet Charm of Protein Binding Sites

Beschreibung

This book is a passionate account of the scientific breakthroughs that led to the solution of the first protein structures and to the understanding of their function at atomic resolution. The book is divided into self-standing chapters that each deal with a protein or protein family. The subject is presented in a fluid, non-technical style that will engage student and scientists in biochemistry, biophysics, molecular and structure biology and physiology.
This book is a passionate account of the scientific breakthroughs that led to the solution of the first protein structures and to the understanding of their function at atomic resolution. The book is divided into self-standing chapters that each deal with a protein or protein family. The subject is presented in a fluid, non-technical style that will engage student and scientists in biochemistry, biophysics, molecular and structure biology and physiology.
Covers the great discoveries of protein crystallography of the 20th century, as told by one of the protagonists Explains the unique selectivity of proteins in the binding of small molecules Addresses the most important questions about protein binding sites

Autor*in

Joseph Yariv

Themen in »The Discreet Charm of Protein Binding Sites«

Allosteric Protein Alpha and Beta Tubulin Dimers Colchicine Binding-site Concanavalin A binding Specificity History of Protein Structure Determination Human Aquaporins Membrane Transport Proteins Protein Structure by X-ray Crystallography Protein-Ligand Interactions Receptors

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“This study is quite probably the inspiration behind ‘The discreet charm’, which is a personal, and passionate story of how proteins interact with other chemical moieties, be it organic molecules or other proteins. … The book is well illustrated, both with copies of original figures from the referenced bibliography, as well as schematic structure figures prepared using Protein Data Bank (PDB) entries. … the book is a pleasure to read.” (Zygmunt Derewenda, Crystallography Reviews, May, 2016)

“Many thanks for your beautifully illustrated and readable book on protein binding sites. Good choice of examples and good coverage.” (Pauline Harrison, The University of Sheffield, Department of Molecular Biology and Biotechnology, UK) 
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