Metabolic Interaction in Infection
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Beschreibung
This book focuses on host–pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
This book focuses on host–pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
State-of-the art guide of metabolism focused on host-pathogen interactions Characterization of the emerging role of immunometabolism during infections Comparative description of microbial auxotrophy and host cell metabolic rewiring by pathogens; Current status and future perspectives on the clinical application of cell metabolism evaluation in infectious contexts
Autor*in
Ricardo Silvestre
Themen in »Metabolic Interaction in Infection«
Host-pathogen interactions Metabolism Microbial auxotrophy Infection Bioenergetics