Häcker Biology of Chlamydia

Biology of Chlamydia

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Beschreibung

The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria – which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell’s defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.


Covers the question of long-term, persistent Chlamydia infection
Broadens your understanding about chlamydial host adaptation
Illustrates the complex mechanisms that determine immune recognition, immunopathology and potentially anti-infective protection
Discusses the question of long-term, persistent Chlamydia infection Provides new insights into chlamydial host adaptation Illustrates the complex mechanisms that determine immune recognition, immunopathology and potentially anti-infective protection

Autor*in

Georg Häcker

Themen in »Biology of Chlamydia«

Chlamydia developmental cycle Chlamydia infections Chlamydia pneumonia Chlamydia trachomatis Cell wall biosynthesis Peptidoglycan infectious diseases

Stimmen zu »Biology of Chlamydia«

Details

ISBN: 9783319712307
Verlag: Springer International Publishing
Erscheinung: 09.07.2018

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