This book provides a selection of essential knowledge on the image-based quantification of biophysical parameters for the purpose of clinical diagnosis. The authors regard clinical imaging scanners as physical measurement systems capable of quantifying intrinsic parameters for depiction of the constitution and biophysical properties of in vivo tissue. On the one hand, this approach supports the development of new methods of imaging highly reproducible, system-independent, and quantitative biomarkers, and these methods receive detailed attention in the book. On the other hand, the reader will also gain a deeper understanding of how physical tissue properties interact with the generation of signals in medical imaging, opening new windows on the intricate and fascinating relationship between the structure and function of living tissues. The book will be of interest to all who recognize the limitations of basing clinical diagnosis primarily on visual inspection of images and who wish to learn more about the diagnostic potential of quantitative and biophysics-based medical imaging markers and the challenges that the paucity of such markers poses for next-generation imaging technologies.
Concisely describes biophysics-based approaches used in quantitative medical imaging
Clarifies the diagnostic potential of these approaches
Elucidates the relationships between tissue properties, imaging technology, and medical applications
Ingolf Sack
Quantitative medical imaging Biophysical tissue properties Medical technology Parameter mapping Imaging technology Biophysics-based medical imaging markers Imaging biomarkers Imaging physics Medical image processing