This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies.
This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.
Luca Marchetti
Computational Systems Biology Deterministic Simulation Hybrid Simulation Reaction-Diffusion Simulation Stochastic Simulation algorithm analysis and problem complexity Systems Biology systems biology
“I will not hesitate to recommend … this book, both as an introductory explanation as well as later on when they are deep in a modeling exercise and need to understand the many subtle yet important variations of stochastic simulation techniques applicable to biological systems.” (Sara Kalvala, Computing Reviews, March, 2018)
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