Non-coding RNAs in the Vasculature
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Beschreibung
This book focuses on the importance of regulatory RNAs in the vasculature. The main topics discussed include the role of regRNAs in vascular development and angiogenesis, ischemic cardiovascular disease and repair mechanisms, diabetic and metabolic vascular disease, atherosclerosis and vascular inflammation, as well as diagnostics of vascular disease using circulating miRNAs. Lastly, it offers an overview of emerging topics such as microvesicle-mediated miRNA cellular trafficking and the vascular importance of long non-coding RNAs. It is an invaluable resource for academics, researchers and students working in the field of vascular biology.
This volume describes important functions and roles of micro RNAs in the vasculature in health, disease, therapeutics and diagnostics. It shows how miRNAs can be used to improve stem cell-based regenerative therapies of cardiovascular diseases; further the role of miRNAs as regulators in lipoprotein metabolism in the liver and reverse cholesterol transport is depicted, as well as their pathological function in diabetes and atherosclerosis. The book discusses the use of circulating miRNAs as disease biomarkers and shows interesting correlations with the amount of detectable miRNAs in the blood and future cardiovascular risks.
This book is edited and written by leading figures in the field and will be an invaluable resource for academics, researchers and students working on non-coding RNAs in biomedicine, physiology and vascular biology.
Depicts the divers roles and functions of non-coding RNAs in the vasculature. Provides knowledge on micro RNAs as biomarkers in cardiovascular disease. Offers insight into the use of miRNAs in stem cell-based regenerative therapies of cardiovascular disease.
Autor*in
Thomas Thum
Themen in »Non-coding RNAs in the Vasculature«
angiogenesis atherosclerosis cardiovascular disease human metabolism lncRNAs microRNAs regulatory RNAs miRNAs and diagnostics vascular development long non-coding RNA microRNA as biomarker ncRNAs role of non-coding RNA noncoding RNAs in vascular cell types Diabetes and miRNA