The Hippocampus from Cells to Systems
Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition
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Beschreibung
The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia.
The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).
The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia.
The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).
This book provides a comprehensive overview of the hippocampus from cells to systems; drawing from neurophysiological, neuroimaging, and neuropsychological research investigations conducted across species. There is no other work, to our knowledge, that brings together in a single source this breadth of coverage of the structure and function of the hippocampus. The reach of this book extends well beyond traditional views of hippocampal function, highlighting contributions of the hippocampus to flexible cognition in a variety of cognitive domains. Hannula and Duff have assembled a group of world-class authors who would not otherwise publish in the same circles, providing readers with a one-stop shop to learn about current and interdisciplinary perspectives on hippocampal structure and function.
Autor*in
Deborah E. Hannula
Themen in »The Hippocampus from Cells to Systems«
Anatomy Flexible Cognition Health, Development, and Aging Neuroimaging Neurophysiology Relational Memory
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“This is a detailed monograph on the neurophysiology of the hippocampus in animals and humans. … I recommend this book to neurologists, neurophysiologists, psychiatrists, psychologists, and neurosurgeons with a strong interest in the hippocampus and its rles in the brain.” (Joseph Grenier, Amazon.com, November, 2017)
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