Microtechnology for Cell Manipulation and Sorting

Beschreibung

This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous two-phase systems as the dominant mechanisms utilized by microfluidic devices to handle biological samples. Each chapter explains the physics of the mechanism at work, and reviews common geometries and devices to help readers decide the type of style of device required for various applications. This book is appropriate for graduate-level biomedical engineering and analytical chemistry students, as well asengineers and scientists working in the biotechnology industry.

Provides comprehensive coverage of technologies that allow single cell and cell aggregate manipulation, which has the potential to significantly influence research on biological matters

Includes examples of cell sorting, such as acoustic, hydrodynamic, and inertial microfluidics

Includes practical information on sample preparation and diagnostics

Autor*in

Wonhee Lee

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