Epstein Barr Virus Volume 2
One Herpes Virus: Many Diseases
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Beschreibung
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Historical reminiscence of Professor Sir Anthony Epstein on the discovery of EBV 50 years ago 32 comprehensive chapters on EBV virology, tumorigenesis and immune control Newest insights on EBV strain variation, the recombinant EBV system and in vivo models of infection Comprehensive account of EBV associated diseases, including autoimmune diseases Update on EBV specific therapies including adoptive T cell transfer and new vaccine formulations Includes supplementary material: sn.pub/extras
Autor*in
Christian Münz
Themen in »Epstein Barr Virus Volume 2«
cell-mediated immune control human tumor virus immunotherapies lymphomas and carcinomas persistent infection infectious diseases