Current Advances in Osteosarcoma
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Beschreibung
Current Advances in Osteosarcoma summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in this field over the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and is the most common histological form of bone cancer. Osteosarcoma accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat.
In order to improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies includingsome based on the molecular and genetic phenotype of the disease. This volume will provide a comprehensive review of these new discoveries in one singular text, which will help move the field forward.
Current Advances in Osteosarcoma edited by Dr. Eugenie S. Kleinerman summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer. It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. To improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. Current Advances in Osteosarcoma summarizes all of these new discoveries in one singular text, which will help move the field forward.
The topics provide a starting block for unified discussions for osteosarcoma researchers in order to move the field forward The volume editor is an internationally recognized leader in the field of sarcomas, particularly osteosarcoma Editors: Kleinerman, Eugenie S. (Ed.) The volume comprehensively covers the biology of osteosarcoma, including seminal discoveries of molecular pathways and genetic alterations that lead to metastasis Includes supplementary material: sn.pub/extras
Autor*in
Eugenie S. Kleinerman, M.D.
Themen in »Current Advances in Osteosarcoma«
bone cancer cancer metastasis osteosarcoma pediatric cancer
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From the book reviews:
“The work is both relevant and timely as no other book fills this particular niche in the field of osteosarcoma. … book is written for students, clinicians, and scientists seeking a review of the biology of osteosarcoma. … Graduate students, medical residents and fellows, and postdoctoral researchers beginning osteosarcoma research projects will find it a very useful introduction to the broad scope of osteosarcoma science. … a worthy addition to the library of all who are interested in osteosarcoma science.” (George Calvert, Doody’s Book Reviews, February, 2015)()