Translational Neuropsychopharmacology

Beschreibung

This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.  
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.  
Translational (neuro)psychopharmacology is the application of basic neuroscience and psychopharmacology to the treatment of psychiatric and neurological disorders - which remain our largest health and socio-economic burden There are currently no books on the subject There are relatively few investigators who have managed to bridge the 'translational gap'; many of them are represented in the current list of possible contributors Includes supplementary material: sn.pub/extras

Autor*in

Trevor W. Robbins

Themen in »Translational Neuropsychopharmacology«

Depression models Psychiatric and neurological disorders Schizophrenia models Translational approaches to anxiety Translational models Translational neuropsychopharmacology psychopharmacology

Stimmen zu »Translational Neuropsychopharmacology«

“This book examines the ‘translational gap’ between animal models of neuropsychiatric disease and human studies. … The intended audience is scientists working on problems related to neuropsychopharmacology. … This is an important addition to the literature on translational neurosciences. It is an important contribution to understanding both the current state of this field and its possible future directions.” (Eric Gausche, Doody's Book Reviews, November, 2016)

Details

Link teilen