Autophagy at the Cell, Tissue and Organismal Level
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Beschreibung
This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
Covers autophagy from the basic mechanisms to its effects at the cell, tissue and organism level Includes an extensive list of antibodies for the study of autophagy Written by experts in the field Includes supplementary material: sn.pub/extras
Autor*in
Eleftherios Karanasios
Themen in »Autophagy at the Cell, Tissue and Organismal Level«
Autophagosome formation Basic mechanisms of autophagy Immunity and autophagy Physiological roles of autophagy Signalling of autophagy processes TORC1 signalling